Ca2+-calmodulin-dependent protein kinase kinase inhibitor
CAS：1173022-21-3
分子式：C19H10N2O3.C2H4O2
分子量：374.35
纯度：98%
存储：Store at -20°C

Background:

STO-609 is a selective and cell-permeable inhibitor of the Ca2+/calmodulin-dependent protein kinase kinase (CaM-KK), with Ki values of 80 and 15 ng/mL for recombinant CaM-KKα and CaM-KKβ, respectively. STO-609 inhibits AMP-activated protein kinase kinase (AMPKK) activity in HeLa cell lysates with an IC50