GSK3326595是一种有效的,选择性的,可逆的蛋白精氨酸甲基转移酶5((PRMT5))抑制剂,具有广泛的抗增殖活性。
CAS:1616392-22-3
分子式:C24H32N6O3
分子量:452.55
纯度:98%
存储:Store at -20°C
Background:
GSK3326595 is a potent, selective, reversible inhibitor of protein arginine methyltransferase 5 (PRMT5) with an IC50 of 6.2 nM.
GSK3326595 (EPZ015938), has entered clinical trials for the treatment of solid tumors and non-Hodgkin’s lymphoma[1].
[1]. WO 2016022605 A1