Hydroflumethiazide is a thiazide diuretic that also inhibits carbonic anhydrase (CA).
CAS:135-09-1
分子式:C8H8F3N3O4S2
分子量:331.3
纯度:98%
存储:Store at -20°C
Background:
Hydroflumethiazide is a thiazide diuretic that also inhibits carbonic anhydrase (CA). It is selective for CAII, VB, VII, IX, XII, and XIV (Kis = 305-235 nM) over CAI, IV, and VI (Kis = 2,840-8,250 nM) and CAIII, VA, and XIII (Kis = >10 µM). Diuretics of the thiazide class, of which hydroflumethiazide is a member, inhibit the renal Na+/Cl- cotransporter. Formulations containing hydroflumethiazide have been used as diuretics.