Lomerizine sulfate (also known as KB-2796) is a relatively new and potent L- and T-type calcium channel blocker used in the treatment of migraine. Lomerizine (0.1 μM and 1 μM) significantly reduces glutamate-induced neurotoxicity in rat cultured retinal neurons. Lomerizine (1 μM) also exhibits protective effects against both the N-methyl-D-aspartate and kainate induced types of neurotoxicity in rat cultured retinal neurons.
纯度:≥98%