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Methotrexate(Abitrexate)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Methotrexate(Abitrexate)图片
CAS NO:59-05-2
包装与价格:
包装价格(元)
100mg电议
200mg电议
500mg电议
10mM * 1mL in DMSO电议

产品名称
MTX, amethopterin, Abitrexate, Rheumatrex, Trexall
产品介绍

生物活性

Methotrexate (Abitrexate)是一种抑制胸苷酸合成酶和从头嘌呤合成的细胞毒剂。

化学数据

目录号A10021
作用机制Inhibitor (抑制剂)
M. Wt454.44
FormulaC20H22N8O5
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.CAS: 59-05-2
SynonymsMTX, amethopterin, Abitrexate, Rheumatrex, Trexall
SMILESCN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O

溶解度

In vitro (25°C)DMSOWarmed: 89 mg/mL (195.84 mM)
WaterInsoluble
EthanolInsoluble
In vivo2% DMSO+30% PEG 300+5% Tween 80+ddH2O4 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM22.01 mL110.03 mL220.05 mL
0.5 mM4.4 mL22.01 mL44.01 mL
1 mM2.2 mL11 mL22.01 mL
5 mM0.44 mL2.2 mL4.4 mL

*The above data is based on the productmolecular weight 454.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.