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ABT-751(E-7010)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
ABT-751(E-7010)图片
CAS NO:141430-65-1
包装与价格:
包装价格(元)
10mg电议
50mg电议
100mg电议
200mg电议
10mM * 1mL in DMSO电议

产品名称
ABT751
产品介绍

生物活性

ABT-751 (E-7010)是一种抗有丝分裂剂,可抑制微管聚合,并在秋水仙碱位点与β-微管蛋白结合。在G2M期阻断细胞周期并诱导凋亡。

靶点信息

Microtubules

化学数据

目录号A10024
作用机制Inhibitor (抑制剂)
M. Wt371.4
FormulaC18H17N3O4S
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.141430-65-1
SynonymsABT751
SMILESCOC1=CC=C(C=C1)S(=O)(=O)NC2=C(N=CC=C2)NC3=CC=C(C=C3)O

溶解度

In vitro (25°C)DMSO71 mg/mL (191.16 mM)
WaterInsoluble
Ethanol12 mg/mL (32.3 mM)
In vivo30% propylene glycol, 5% Tween 80, 65% D5W14 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM26.93 mL134.63 mL269.25 mL
0.5 mM5.39 mL26.93 mL53.85 mL
1 mM2.69 mL13.46 mL26.93 mL
5 mM0.54 mL2.69 mL5.39 mL

*The above data is based on the productmolecular weight 371.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.