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Amlodipine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Amlodipine图片
CAS NO:88150-42-9
包装与价格:
包装价格(元)
500mg电议
10mM * 1mL in DMSO电议

产品名称
Istin, Norvasc, Caduet
产品介绍

生物活性

Amlodipine是一种L型钙通道阻滞剂,具有降压作用。它抑制去极化大鼠主动脉中Ca2 +诱导的收缩(IC50 = 1.9 nM),并在心血管疾病中显示出血管保护作用。

化学数据

目录号A10068
作用机制Blocker (阻断剂)
M. Wt408.9
FormulaC20H25ClN2O5
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.88150-42-9
SynonymsIstin, Norvasc, Caduet
SMILESCCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN

溶解度

In vitroDMSO71 mg/mL (173.64 mM)
WaterInsoluble
Ethanol71 mg/mL (173.64 mM)
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM24.46 mL122.28 mL244.56 mL
0.5 mM4.89 mL24.46 mL48.91 mL
1 mM2.45 mL12.23 mL24.46 mL
5 mM0.49 mL2.45 mL4.89 mL

*The above data is based on the productmolecular weight 408.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.