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Apixaban(BMS-562247-01)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Apixaban(BMS-562247-01)图片
CAS NO:503612-47-3
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议
100mg电议
10mM * 1mL in DMSO电议

产品名称
BMS-562247-01
产品介绍

生物活性

Apixaban (BMS-562247-01)是一种抗凝剂,用于预防静脉血栓栓塞和静脉血栓栓塞事件。

靶点信息

Factor Xa (human) (Cell-free assay)Factor Xa (rabbit) (Cell-free assay)
0.08 nM(Ki)0.17 nM(Ki)

化学数据

目录号A10082
作用机制Inhibitor (抑制剂)
M. Wt459.5
FormulaC25H25N5O4
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.503612-47-3
SynonymsBMS-562247-01
SMILESCOC1=CC=C(C=C1)N2C3=C(CCN(C3=O)C4=CC=C(C=C4)N5CCCCC5=O)C(=N2)C(=O)N

溶解度

In vitro (25°C)DMSO17 mg/mL (36.99 mM)
WaterInsoluble
EthanolInsoluble
In vivo30% PEG 400+0.5% Tween 80+5% Propylene glycol28 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM21.76 mL108.81 mL217.63 mL
0.5 mM4.35 mL21.76 mL43.53 mL
1 mM2.18 mL10.88 mL21.76 mL
5 mM0.44 mL2.18 mL4.35 mL

*The above data is based on the productmolecular weight 459.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.