生物活性
Artemisinin及其衍生物是一类药物，在所有当前针对恶性疟原虫疟疾的药物中具有最快的作用。
靶点信息
化学数据
| 目录号 | A10086 |
| M. Wt | 282.3 |
| Formula | C15H22O5 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 63968-64-9 |
| Synonyms | Coartem,Qinghaosu |
| SMILES | C[C@@H]1CC[C@H]2[C@H](C(=O)O[C@H]3[C@@]24[C@H]1CCC(O3)(OO4)C)C |
溶解度
| In vitro | DMSO | 55 mg/mL (194.81 mM) |
| Water | Insoluble |
| Ethanol | 23 mg/mL (81.46 mM) |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 35.42 mL | 177.12 mL | 354.23 mL |
| 0.5 mM | 7.08 mL | 35.42 mL | 70.85 mL |
| 1 mM | 3.54 mL | 17.71 mL | 35.42 mL |
| 5 mM | 0.71 mL | 3.54 mL | 7.08 mL |
*The above data is based on the productmolecular weight 282.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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