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Biochanin A(4-Methylgenistein)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Biochanin A(4-Methylgenistein)图片
CAS NO:491-80-5
包装与价格:
包装价格(元)
200mg电议
500mg电议
10mM * 1mL in DMSO电议

产品名称
4-Methylgenistein
产品介绍

生物活性

Biochanin A (4-Methylgenistein)是一种抗增殖和抗炎剂,可抑制iNOS的表达和脂多糖(LPS)诱导的巨噬细胞中一氧化氮的产生。此外,Biochanin A还具有阻断IκBα和p38 MAPK磷酸化的能力,从而阻止了NF-κB的活化。此外,已观察到生物chanin A抑制IL-6,IL-1β和TNF-α的产生。

靶点信息

FAAH (rat)FAAH (mouse)FAAH (human)EGFR
1.4 μM1.8 μM2.4 μM91.5 μM

化学数据

目录号A10146
M. Wt284.3
FormulaC16H12O5
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.491-80-5
Synonyms4-Methylgenistein
SMILESCOC1=CC=C(C=C1)C2=COC3=CC(=CC(=C3C2=O)O)O

溶解度

In vitroDMSO51 mg/mL (179.41 mM)
WaterInsoluble
Ethanol8 mg/mL (28.14 mM)
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM35.17 mL175.87 mL351.74 mL
0.5 mM7.03 mL35.17 mL70.35 mL
1 mM3.52 mL17.59 mL35.17 mL
5 mM0.7 mL3.52 mL7.03 mL

*The above data is based on the productmolecular weight 284.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.