生物活性
Bleomycin Sulfate硫酸博来霉素是一种糖肽类抗生素，也是一种鳞状细胞癌(SCC)抗癌剂。
靶点信息
化学数据
| 目录号 | A10152 |
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 1512.6 |
| Formula | C55H85N17O25S4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 9041-93-4 |
| Synonyms | Blenoxane |
| SMILES | CC1=C(N=C(N=C1N)[C@H](CC(=O)N)NC[C@H](C(=O)N)N)C(=O)N[C@@H](C(C2=CN=CN2)O[C@@H]3[C@@H]([C@@H]([C@H]([C@H](O3)CO)O)O)O[C@@H]4[C@H]([C@H]([C@@H]([C@H](O4)CO)O)OC(=O)N)O)C(=O)N[C@@H](C)[C@@H]([C@@H](C)C(=O)N[C@H]([C@@H](C)O)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O |
溶解度
| In vitro | DMSO | Warmed: 93 mg/mL (61.48 mM) |
| Water | 93 mg/mL (61.48 mM) |
| Ethanol | Insoluble |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 6.61 mL | 33.06 mL | 66.11 mL |
| 0.5 mM | 1.32 mL | 6.61 mL | 13.22 mL |
| 1 mM | 0.66 mL | 3.31 mL | 6.61 mL |
| 5 mM | 0.13 mL | 0.66 mL | 1.32 mL |
*The above data is based on the productmolecular weight 1512.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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