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Bortezomib(Velcade)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Bortezomib(Velcade)图片
CAS NO:179324-69-7
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
100mg电议
10mM * 1mL in DMSO电议

产品名称
MG-341, PS-341
产品介绍

生物活性

Bortezomib (Velcade)是26S蛋白酶体的高度选择性,可逆抑制剂。

靶点信息

20S proteasome (Cell-free assay)
0.6 nM(Ki)

化学数据

目录号A10160
作用机制Inhibitor (抑制剂)
M. Wt384.2
FormulaC19H25BN4O4
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.179324-69-7
SynonymsMG-341, PS-341
SMILESB([C@H](CC(C)C)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)(O)O

溶解度

In vitro (25°C)DMSO66 mg/mL (171.77 mM)
WaterInsoluble
EthanolInsoluble
In vivo2% DMSO+30% PEG 300+ddH2O4 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM26.03 mL130.14 mL260.28 mL
0.5 mM5.21 mL26.03 mL52.06 mL
1 mM2.6 mL13.01 mL26.03 mL
5 mM0.52 mL2.6 mL5.21 mL

*The above data is based on the productmolecular weight 384.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.