potent deubiquitinase enzyme inhibitor
CAS:924296-17-3
分子式:C16H9N5O
分子量:287.28
纯度:98%
存储:Store at -20°C
Background:
DUBs-IN-3 is a potent deubiquitinase (USP) enzyme inhibitor extracted from reference compound 22c with an IC50 of 0.56 μM for USP8.
参考文献:
[1]. Colombo M, et al. Synthesis and biological evaluation of 9-oxo-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile analogues as potential inhibitors of deubiquitinating enzymes. ChemMedChem. 2010 Apr 6;5(4):552-8.