H-151是一种高效、选择性、共价的STING拮抗剂,能够降低TBK1的磷酸化,抑制人STING的棕榈酰化。
CAS:941987-60-6
分子式:C17H17N3O
分子量:279.34
纯度:98%
存储:Store at -20°C
Background:
H-151 is a highly potent, selective and covalent antagonist of STING, reduces TBK1 phosphorylation and suppresses human STING palmitoylation[1].
STING[1]
[1]. Haag SM, et al. Targeting STING with covalent small-molecule inhibitors. Nature. 2018 Jul;559(7713):269-273.