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TNF-αAntagonist
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
TNF-αAntagonist图片
CAS NO:199999-60-5
规格:98%
分子量:1226.4
包装与价格:
包装价格(元)
500ug电议
1mg电议
5mg电议

产品介绍
TNF-α antagonist is an exocyclic peptide that mimics the critical TNF-α recognition loop on TNF receptor I complex and, thus, prevents ligand interaction with the receptor.
CAS:199999-60-5
分子式:C58H71N11O15S2
分子量:1226.4
纯度:98%
存储:Store at -20°C

Background:

TNF-α antagonist is an exocyclic peptide that mimics the critical TNF-α recognition loop on TNF receptor I complex and, thus, prevents ligand interaction with the receptor. By blocking the TNF receptor ligand contact site, this peptide interferes with both activating receptor activator of NF-κB (RANK) and TNF-α’s recruitment and activation of osteoclasts. TNF-α antagonist has been used to block bone resorption in the study of systemic bone loss in rheumatoid arthritis and inflammatory bone destruction.