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Anti-Inflammatory Peptide 1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Anti-Inflammatory Peptide 1图片
CAS NO:118850-71-8
规格:98%
分子量:1079.33
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品介绍
PLA2 inhibitor
CAS:118850-71-8
分子式:C45H82N12O14S2
分子量:1079.33
纯度:98%
存储:Store at -20°C

Background:

Anti-Inflammatory Peptide 1 (C45H82N12O14S2), with the sequence H-Met-Gln-Met-Lys-Lys-Val-Leu-Asp-Ser-OH, belongs to the group of synthetic oligopeptides corresponding to a region of high amino-acid sequence similarity between uteroglobin and lipocortin I. The name 'antiflammins' is proposed for those peptides, which are valuable models for the development of novel anti-inflammatory agents of therapeutic importance. Anti-inflammatory peptide 1 possesses a potent anti-inflammatory activity in vivo and is a strong inhibitor of phospholipase A2 (PLA2), whose increased presence and activity results in inflammation and pain at certain bodily sites.


参考文献:
1. Argiolas A, Pisano JJ (November 1983). "Facilitation of phospholipase A2 activity by mastoparans, a new class of mast cell degranulating peptides from wasp venom". J. Biol. Chem. 258 (22): 13697–702.