生物活性
Ciclopirox是一种合成的抗真菌药物。它可以抑制酵母糠醛马拉丝霉的生长,并通过中断Na+K+ ATPase来抑制膜转移系统,从而发挥作用。
靶点信息
化学数据
目录号 | A10213 |
M. Wt | 207.3 |
Formula | C12H17NO2 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for36 months. In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
CAS No. | 29342-05-0 |
Synonyms | Batrafen, Loprox, Mycoster, Stieprox, HOE 296b |
SMILES | CC1=CC(=O)N(C(=C1)C2CCCCC2)O |
溶解度
In vitro | DMSO | 36 mg/mL (173.68 mM) |
Water | Insoluble |
Ethanol | 36 mg/mL (173.68 mM) |
*<1 mg/ml means slightly soluble or insoluble. *Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
0.1 mM | 48.24 mL | 241.2 mL | 482.39 mL |
0.5 mM | 9.65 mL | 48.24 mL | 96.48 mL |
1 mM | 4.82 mL | 24.12 mL | 48.24 mL |
5 mM | 0.96 mL | 4.82 mL | 9.65 mL |
*The above data is based on the productmolecular weight 207.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.