生物活性
Divalproex sodium钠由1:1摩尔关系的丙戊酸钠和丙戊酸的肠溶包衣化合物组成,是一种HDAC抑制剂。它在英国,加拿大和美国用于治疗躁郁症的躁狂发作。
靶点信息
化学数据
目录号 | A10321 |
M. Wt | 310.41 |
Formula | C8H16O2.C8H15O2.Na |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for36 months. In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
CAS No. | 76584-70-8 |
Synonyms | Valproate semisodium |
SMILES | CCCC(CCC)C(=O)O.CCCC(CCC)C(=O)[O-].[Na+] |
溶解度
In vitro | DMSO | 61 mg/mL (196.51 mM) |
Water | 61 mg/mL (196.51 mM) |
Ethanol | 61 mg/mL (196.51 mM) |
*<1 mg/ml means slightly soluble or insoluble. *Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
0.1 mM | 32.22 mL | 161.08 mL | 322.15 mL |
0.5 mM | 6.44 mL | 32.22 mL | 64.43 mL |
1 mM | 3.22 mL | 16.11 mL | 32.22 mL |
5 mM | 0.64 mL | 3.22 mL | 6.44 mL |
*The above data is based on the productmolecular weight 310.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.