生物活性
Floxuridine是一种抗肿瘤药，属于抗代谢物，是一种MDCK/PEPT1抑制剂。
靶点信息
化学数据
| 目录号 | A10392 |
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 246.2 |
| Formula | C9H11FN2O5 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 50-91-9 |
| Synonyms | 5-fluorodeoxyuridine, Fluorodeoxyuridine, FUDR, FdUrd, Floxuridin, FAMP |
| SMILES | C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)F)CO)O |
溶解度
| In vitro | DMSO | 43 mg/mL (174.66 mM) |
| Water | 43 mg/mL (174.66 mM) |
| Ethanol | 9 mg/mL |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 40.62 mL | 203.09 mL | 406.17 mL |
| 0.5 mM | 8.12 mL | 40.62 mL | 81.23 mL |
| 1 mM | 4.06 mL | 20.31 mL | 40.62 mL |
| 5 mM | 0.81 mL | 4.06 mL | 8.12 mL |
*The above data is based on the productmolecular weight 246.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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