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C-1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:84468-24-6
规格:98%
分子量:277.34
包装与价格:
包装价格(元)
10mg电议
50mg电议

产品介绍
protein kinase C inhibitor
CAS:84468-24-6
分子式:C13H15N3O2S
分子量:277.34
纯度:98%
存储:Store at -20°C

Background:

HA-100 is an inhibitor of cGMP-dependent protein kinase (PKG), cAMP-dependent protein kinase (PKA), protein kinase C (PKC) and MLC-kinase with IC50s of 4, 8, 12 and 240 μM, respectively[1].


HA-100 inhibits MLC-kinase and PKC competitively with respect to ATP, and the Ki values are 61 and 6.5 μM, respectively[1].


参考文献:
[1]. Hagiwara M, et al. Selective modulation of calcium-dependent myosin phosphorylation by novel protein kinase inhibitors, isoquinolinesulfonamide derivatives. Mol Pharmacol. 1987 Jul;32(1):7-12.