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Erianin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Erianin图片
CAS NO:95041-90-0
规格:98%
分子量:318.36
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议

产品介绍
Erianin,常用作退烧药和止疼剂,能够抑制吲哚胺-2,3-双加氧酶(IDO)诱导的肿瘤血管生成。
CAS:95041-90-0
分子式:C18H22O5
分子量:318.36
纯度:98%
存储:Store at -20°C

Background:

Erianin, often used as an antipyretic and analgesic agent, could inhibit IDO-induced tumor angiogenesis.


Erianin is often used as antipyretic and analgesic agent. Erianin belongs to bibenzyl derivatives in structure, with the activity of anti-virus, anti-bacterial, as well as anti-benign prostatic hyperplasia. Erianin has obvious damage on 2LL-IDO cells, Erianin basically has no cytotoxicity on human normal liver cell line L02, and cell viability is maintained at around 85%[1]. Erianin inhibits the growth of HeLa cells and induces apoptosis in a dose? and time?dependent manner, inducing cell cycle arrest at the G2/M stage. Erianin treatment also increases the expression of Bax and caspase?3, but decreases levels of Bcl?2 and phosphorylated?ERK1/2[2].



[1]. Su C, et al. Erianin inhibits indoleamine 2, 3-dioxygenase -induced tumor angiogenesis. Biomed Pharmacother. 2017 Apr;88:521-528. [2]. Li M, et al. Erianin inhibits human cervical cancer cell through regulation of tumor protein p53 via the extracellular signal-regulated kinase signaling pathway. Oncol Lett. 2018 Oct;16(4):5006-5012.