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9-cis Retinal
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
9-cis Retinal图片
CAS NO:514-85-2
规格:98%
分子量:284.4
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
9-cis Retinal is a natural retinoid that is produced by oxidation of 9-cis retinol by cis-retinol dehydrogenase (cRDH).
CAS:514-85-2
分子式:C20H28O
分子量:284.4
纯度:98%
存储:Store at -20°C

Background:

9-cis Retinal is a natural retinoid that is produced by oxidation of 9-cis retinol by cis-retinol dehydrogenase (cRDH). It binds to cellular retinol-binding protein-I (CRBP-I) and CRBP-II (Kds = 8 and 5 nM, respectively) and to cellular retinaldehyde-binding protein (CRALBP; Kd = 53.3 nM). In vitro, 9-cis retinal inhibits differentiation of RCJ C5.18 chondrogenic cells into cartilage (IC50 = 8 nM). In vivo, it rescues cone electroretinogram (ERG) responses in Irbp-/- mice, which lack interphotoreceptor retinoid-binding protein and have diminished cone responses, when administered at a dose of 0.375 mg.