inhibits adenosine triphosphatase activity
CAS：1642288-47-8
分子式：C15H19N3O2
分子量：273.33
纯度：98%
存储：Store at -20°C

Background:

MYK-461 is a small molecular chemical that reduces contractility by decreasing the adenosine triphosphatase activity of the cardiac myosin heavy chain.

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MYK-461 reduced ATPase activity in a dose-dependent manner with IC50 value of 0.3 mM after treatment of mouse cardiac myofibrils. MYK-461 (>10 mM) decreased the maximal ATPase rate by