Darodipine, formerly known as PY-108068, is a potent a calcium antagonist. Darodipine dose-depentently blocks I(Ca,L) in rat isolated cardiomyocytes. Darodipine exerts protective effects against free-radical-induced electrophysiological alterations independently of its calcium antagonistic properties; this effect is possibly due to trapping of specific radical species. . References: Sannita WG, Garbarino S, Gesino D, Massimilla S, Ogliastro C. Plasma concentration and CNS effects of Ca antagonists darodipine and nimodipine after single-dose oral administration to healthy volunteers. Neuropsychobiology. 1999 Sep;40(3):158-70. PubMed PMID: 10494052.

纯度：≥98%

CAS：72803-02-2