Rebeccamycin is an indolocarbazole antibiotic produced by S.
CAS：93908-02-2
分子式：C27H21Cl2N3O7
分子量：570.4
纯度：98%
存储：Store at -20°C

Background:

Rebeccamycin is an indolocarbazole antibiotic produced by S. aerocolonigenes ATCC39243 that weakly inhibits DNA topoisomerase I. It is cytotoxic to human lung adenocarcinoma, colon carcinoma, and nasopharyngeal carcinoma cell lines (IC50s range from 0.4-98 µM), producing single-strand breaks in the DNA of these tumor cells.