生物活性
Kaempferol被发现抑制Ki为0.3-0.5 μM的牛主动脉肌球蛋白轻链激酶，并且还被发现通过新的ERK-NFκB-cMyc-p21途径抑制VEGF表达和体外血管生成。
化学数据
| 目录号 | A10495 |
| 作用机制 | Inhibitor (抑制剂), Agonist (激动剂) |
| M. Wt | 286.2 |
| Formula | C15H10O6 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 520-18-3 |
| SMILES | C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O |
溶解度
| In vitro | DMSO | Warmed: 53 mg/mL (185.17 mM) |
| Water | Insoluble |
| Ethanol | 3 mg/mL (10.48 mM) |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 34.94 mL | 174.7 mL | 349.41 mL |
| 0.5 mM | 6.99 mL | 34.94 mL | 69.88 mL |
| 1 mM | 3.49 mL | 17.47 mL | 34.94 mL |
| 5 mM | 0.7 mL | 3.49 mL | 6.99 mL |
*The above data is based on the productmolecular weight 286.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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