A key intermediate in the ethylmalonyl-CoA pathway for carbon metabolism
CAS：6049-57-6
分子式：C26H42N7O19P3S
分子量：881.6
纯度：98%
存储：Store at -20°C

Background:

Ethylmalonyl coenzyme A (CoA) is a key intermediate in the ethylmalonyl-CoA pathway for carbon metabolism in certain bacteria, such as M. extorquens, which uses this pathway when grown on ethylamine.1,2 It is produced from crotonyl-CoA by crotonyl-CoA reductase/carboxylase and modified by ethylmalonyl-CoA mutase to make methylsuccinyl-CoA.

Reference

1. Good, N.M., Martinez-Gomez, N.C., Beck, D.A.C., et al. Ethylmalonyl coenzyme A mutase operates as a metabolic control point in Methylobacterium extorquens AM1 J. Bacteriol. 197(4), 727-735 (2015).
2. Anthony, C. How half a century of research was required to understand bacterial growth on C1 and C2 compounds; the story of the serine cycle and the ethylmalonyl-CoA pathway Sci. Prog. 94(Pt 2), 109-137 (2011).