生物活性
Metformin HCl降低肝细胞中高血糖症，主要通过抑制肝糖原的产生（肝脏糖异生作用)发挥作用。
靶点信息
化学数据
| 目录号 | A10573 |
| M. Wt | 165.6 |
| Formula | C4H12ClN5 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 1115-70-4 |
| Synonyms | Glucophage, Riomet, Diabex |
| SMILES | CN(C)C(=N)N=C(N)N.Cl |
溶解度
| In vitro | DMSO | Insoluble |
| Water | Warmed: 30 mg/mL (181.14 mM) |
| Ethanol | Insoluble |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 60.39 mL | 301.93 mL | 603.86 mL |
| 0.5 mM | 12.08 mL | 60.39 mL | 120.77 mL |
| 1 mM | 6.04 mL | 30.19 mL | 60.39 mL |
| 5 mM | 1.21 mL | 6.04 mL | 12.08 mL |
*The above data is based on the productmolecular weight 165.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
m.cnreagent.com