生物活性
Nobiletin (Hexamethoxyflavone)是一种化学化合物。它是一种O-甲基化黄酮，一种从柑桔皮中分离的类黄酮，就像橘子一样。发现诺比列汀在体外和体内具有抗炎和抗肿瘤的侵袭，增殖和转移。还发现了Nobiletin可能抑制软骨降解。
靶点信息
化学数据
| 目录号 | A10651 |
| M. Wt | 402.4 |
| Formula | C21H22O8 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 478-01-3 |
| Synonyms | Hexamethoxyflavone |
| SMILES | COC1=C(C=C(C=C1)C2=CC(=O)C3=C(O2)C(=C(C(=C3OC)OC)OC)OC)OC |
溶解度
| In vitro | DMSO | 70 mg/mL (173.95 mM) |
| Water | Insoluble |
| Ethanol | 3 mg/mL (7.45 mM) |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 24.85 mL | 124.25 mL | 248.51 mL |
| 0.5 mM | 4.97 mL | 24.85 mL | 49.7 mL |
| 1 mM | 2.49 mL | 12.43 mL | 24.85 mL |
| 5 mM | 0.5 mL | 2.49 mL | 4.97 mL |
*The above data is based on the productmolecular weight 402.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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