生物活性
Phloretin (Dihydronaringenin)是通过SGLT1和SGLT2抑制葡萄糖向细胞内的主动转运，尽管这种抑制作用比其糖苷phlorizin弱。
靶点信息
化学数据
| 目录号 | A10723 |
| M. Wt | 274.3 |
| Formula | C15H14O5 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 60-82-2 |
| Synonyms | Dihydronaringenin, Phloretol |
| SMILES | C1=CC(=CC=C1CCC(=O)C2=C(C=C(C=C2O)O)O)O |
溶解度
| In vitro | DMSO | 46 mg/mL (167.71 mM) |
| Water | Insoluble |
| Ethanol | 46 mg/mL (167.71 mM) |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 36.46 mL | 182.28 mL | 364.56 mL |
| 0.5 mM | 7.29 mL | 36.46 mL | 72.91 mL |
| 1 mM | 3.65 mL | 18.23 mL | 36.46 mL |
| 5 mM | 0.73 mL | 3.65 mL | 7.29 mL |
*The above data is based on the productmolecular weight 274.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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