SB 221284 is potent, selective 5-HT2C/2B receptor antagonist. SB 221284 are pKis are 6.4, 7.9 and 8.6 for 5-HT2A, 2B and 2C receptors respectively. References: Takeuchi K, Mohammad S, Ozaki T, Morioka E, Kawaguchi K, Kim J, Jeong B, Hong JH, Lee KJ, Ikeda M. Serotonin-2C receptor involved serotonin-induced Ca2+ mobilisations in neuronal progenitors and neurons in rat suprachiasmatic nucleus. Sci Rep. 2014 Feb 17;4:4106. doi: 10.1038/srep04106. PubMed PMID: 24531181; PubMed Central PMCID: PMC3925950.

纯度：≥98%

CAS：196965-14-7