生物活性
Polydatin (Piceid)通过改善微循环和抑制血小板聚集来保护脑细胞免受缺血性损伤。 此外,白蛋白抑制脂多糖刺激的内皮细胞中ICAM-1的表达。 它还会减弱白细胞和内皮细胞之间的粘附。
靶点信息
化学数据
目录号 | A10741 |
作用机制 | Inhibitor (抑制剂) |
M. Wt | 390.4 |
Formula | C20H22O8 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for36 months. In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
CAS No. | 65914-17-2 |
Synonyms | Piceid, 3,4,5-Tsg, 3,4,5-Trihydroxystilbene-3-beta-monoglucoside |
SMILES | C1=CC(=CC=C1/C=C/C2=CC(=CC(=C2)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O)O |
溶解度
In vitro | DMSO | 69 mg/mL (176.75 mM) |
Water | Insoluble |
Ethanol | Insoluble |
*<1 mg/ml means slightly soluble or insoluble. *Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
0.1 mM | 25.61 mL | 128.07 mL | 256.15 mL |
0.5 mM | 5.12 mL | 25.61 mL | 51.23 mL |
1 mM | 2.56 mL | 12.81 mL | 25.61 mL |
5 mM | 0.51 mL | 2.56 mL | 5.12 mL |
*The above data is based on the productmolecular weight 390.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.