生物活性
Rifapentine (Priftin)是一种用于治疗肺结核的抗生素药物。
靶点信息
| DNA-dependent RNA polymerase | | | | |
| | | | |
化学数据
| 目录号 | A10792 |
| M. Wt | 877.0 |
| Formula | C47H64N4O12 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 61379-65-5 |
| Synonyms | Cyclopentylrifampicin |
| SMILES | C[C@H]1/C=C/C=C(\C(=O)NC\2=C(C3=C(C(=C4C(=C3C(=O)/C2=C/NN5CCN(CC5)C6CCCC6)C(=O)[C@](O4)(O/C=C/[C@@H]([C@H]([C@H]([C@@H]([C@@H]([C@@H]([C@H]1O)C)O)C)OC(=O)C)C)OC)C)C)O)O)/C |
溶解度
| In vitro | DMSO | 85 mg/mL (96.92 mM) |
| Water | Insoluble |
| Ethanol | 14 mg/mL (15.96 mM) |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 11.4 mL | 57.01 mL | 114.03 mL |
| 0.5 mM | 2.28 mL | 11.4 mL | 22.81 mL |
| 1 mM | 1.14 mL | 5.7 mL | 11.4 mL |
| 5 mM | 0.23 mL | 1.14 mL | 2.28 mL |
*The above data is based on the productmolecular weight 877.0 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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