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SB 431542
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
SB 431542图片
CAS NO:301836-41-9
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议
100mg电议
10mM * 1mL in DMSO电议

产品名称
SB-431542, SB431542
产品介绍

生物活性

SB 431542是转化生长因子-β超家族I型激活素受体样激酶(ALK)受体ALK4,ALK5和ALK7的有效抑制剂。

靶点信息

ALK4 (Cell-free assay)ALK7 (Cell-free assay)ALK5 (Cell-free assay)
N/A94 nM

化学数据

目录号A10826
作用机制Inhibitor (抑制剂)
M. Wt384.4
FormulaC22H16N4O3
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.301836-41-9
SynonymsSB-431542, SB431542
SMILESC1OC2=C(O1)C=C(C=C2)C3=C(NC(=N3)C4=CC=C(C=C4)C(=O)N)C5=CC=CC=N5

溶解度

In vitro (25°C)DMSO75 mg/mL (195.11 mM)
WaterInsoluble
Ethanol3 mg/mL (7.8 mM)
In vivo2% DMSO+30% PEG 300+ddH2O4 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM26.01 mL130.07 mL260.15 mL
0.5 mM5.2 mL26.01 mL52.03 mL
1 mM2.6 mL13.01 mL26.01 mL
5 mM0.52 mL2.6 mL5.2 mL

*The above data is based on the productmolecular weight 384.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.