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Sophocarpine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Sophocarpine图片
CAS NO:6483-15-4
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议
100mg电议
10mM * 1mL in DMSO电议

产品介绍

生物活性

Sophocarpine是人类ether-à-go-go相关基因(HERG)抑制剂,IC(50)为0.2 mM。可以逆转异丙肾上腺素引起的心律失常并抑制I(Na),I(CaL)和I(Kr)电流。槐角果碱的电生理作用类似于胺碘酮,可能被认为是预期的抗心律失常药。

靶点信息

化学数据

目录号A10857
M. Wt246.4
FormulaC15H22N2O
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.6483-15-4
SMILESC1C[C@H]2CN3[C@H](CC=CC3=O)[C@@H]4[C@H]2N(C1)CCC4

溶解度

In vitroDMSO47 mg/mL (190.78 mM)
Water6 mg/mL (24.35 mM)
Ethanol47 mg/mL (190.78 mM)
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM40.58 mL202.92 mL405.84 mL
0.5 mM8.12 mL40.58 mL81.17 mL
1 mM4.06 mL20.29 mL40.58 mL
5 mM0.81 mL4.06 mL8.12 mL

*The above data is based on the productmolecular weight 246.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.