生物活性
Vinorelbine (Navelbine)是第一个5?NOR半合成长春花生物碱。它是通过半合成从玫瑰色长春花，长春花中提取的生物碱中获得的。
化学数据
| 目录号 | A10976 |
| M. Wt | 778.9 |
| Formula | C45H54N4O8 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 71486-22-1 |
| SMILES | CCC1=C[C@H]2C[C@@](C3=C(CN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)[C@]78CCN9[C@H]7[C@@](C=CC9)([C@H]([C@@]([C@@H]8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC |
溶解度
| In vitro | DMSO | 99 mg/mL (91.73 mM) |
| Water | Warmed: 99 mg/mL (91.73 mM) |
| Ethanol | Warmed: 99 mg/mL (91.73 mM) |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 12.84 mL | 64.19 mL | 128.39 mL |
| 0.5 mM | 2.57 mL | 12.84 mL | 25.68 mL |
| 1 mM | 1.28 mL | 6.42 mL | 12.84 mL |
| 5 mM | 0.26 mL | 1.28 mL | 2.57 mL |
*The above data is based on the productmolecular weight 778.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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