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XAV 939
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
XAV 939图片
CAS NO:284028-89-3
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议
100mg电议
10mM * 1mL in DMSO电议

产品名称
XAV939, XAV-939
产品介绍

生物活性

XAV 939是TNKS抑制剂(TNKS1和TNKS2的IC50值分别为0.011和0.004μM)。

靶点信息

TNKS2 (Cell-free assay)TNKS1 (Cell-free assay)
4 nM11 nM

化学数据

目录号A10994
作用机制Inhibitor (抑制剂)
M. Wt312.3
FormulaC14H11F3N2OS
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.284028-89-3
SynonymsXAV939, XAV-939
SMILESC1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F

溶解度

In vitro (25°C)DMSO12 mg/mL (38.42 mM)
WaterInsoluble
EthanolInsoluble
In vivo4% DMSO+corn oil1 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM32.02 mL160.1 mL320.2 mL
0.5 mM6.4 mL32.02 mL64.04 mL
1 mM3.2 mL16.01 mL32.02 mL
5 mM0.64 mL3.2 mL6.4 mL

*The above data is based on the productmolecular weight 312.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.