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XL184 free base(Cabozantinib)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
XL184 free base(Cabozantinib)图片
CAS NO:849217-68-1
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议
100mg电议
10mM * 1mL in DMSO电议

产品名称
BMS-907351
产品介绍

生物活性

XL184 free base (Cabozantinib)是设计用来抑制多种受体酪氨酸激酶(特别是MET和VEGFR2)的小分子。

化学数据

目录号A10996
作用机制Inhibitor (抑制剂)
M. Wt501.5
FormulaC28H24FN3O5
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.849217-68-1
SynonymsBMS-907351
SMILESCOC1=CC2=C(C=CN=C2C=C1OC)OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)F

溶解度

In vitro (25°C)DMSO92 mg/mL (183.44 mM)
WaterInsoluble
EthanolInsoluble
In vivo2% DMSO+30% PEG 300+5% Tween 80+ddH2O4 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM19.94 mL99.7 mL199.4 mL
0.5 mM3.99 mL19.94 mL39.88 mL
1 mM1.99 mL9.97 mL19.94 mL
5 mM0.4 mL1.99 mL3.99 mL

*The above data is based on the productmolecular weight 501.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.