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ZSTK474
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
ZSTK474图片
CAS NO:475110-96-4
包装与价格:
包装价格(元)
10mg电议
50mg电议
100mg电议
10mM * 1mL in DMSO电议

产品介绍

生物活性

ZSTK474是I类磷脂酰肌醇3激酶同工型的ATP竞争性抑制剂。

靶点信息

PI3Kδ (Cell-free assay)PI3Kα (Cell-free assay)PI3K (Cell-free assay)PI3Kβ (Cell-free assay)PI3Kγ (Cell-free assay)
4.6 nM16 nM37 nM44 nM49 nM

化学数据

目录号A11014
作用机制Inhibitor (抑制剂)
M. Wt417.4
FormulaC19H21F2N7O2
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.475110-96-4
SMILESC1COCCN1C2=NC(=NC(=N2)N3C4=CC=CC=C4N=C3C(F)F)N5CCOCC5

溶解度

In vitro (25°C)DMSO20 mg/mL (47.91 mM)
WaterInsoluble
EthanolInsoluble
In vivo0.5% hydroxyethyl cellulose28 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM23.96 mL119.79 mL239.58 mL
0.5 mM4.79 mL23.96 mL47.92 mL
1 mM2.4 mL11.98 mL23.96 mL
5 mM0.48 mL2.4 mL4.79 mL

*The above data is based on the productmolecular weight 417.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.