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CCT128930
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CCT128930图片
CAS NO:885499-61-6
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议
100mg电议
10mM * 1mL in DMSO电议

产品名称
CCT-128930
产品介绍

生物活性

CCT128930是一种具有ATP竞争性的AKT抑制剂,是一种有效的高级吡咯并嘧啶铅化合物,相对于PKA表现出对AKT的选择性,可通过靶向单个氨基酸差异实现。

靶点信息

Akt2 (Cell-free assay)p70 S6K (Cell-free assay)PKA (Cell-free assay)
6 nM120 nM168 nM

化学数据

目录号A11031
作用机制Inhibitor (抑制剂)
M. Wt341.8
FormulaC18H20ClN5
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.885499-61-6
SynonymsCCT-128930
SMILESC1CN(CCC1(CC2=CC=C(C=C2)Cl)N)C3=NC=NC4=C3C=CN4

溶解度

In vitro (25°C)DMSO59 mg/mL (172.59 mM)
WaterInsoluble
Ethanol5 mg/mL (14.63 mM)
In vivo2% DMSO+30% PEG 300+2% Tween 80+ddH2O3 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM29.26 mL146.28 mL292.57 mL
0.5 mM5.85 mL29.26 mL58.51 mL
1 mM2.93 mL14.63 mL29.26 mL
5 mM0.59 mL2.93 mL5.85 mL

*The above data is based on the productmolecular weight 341.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.