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Triciribine phosphate(NSC-280594)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Triciribine phosphate(NSC-280594)图片
CAS NO:61966-08-3
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议
100mg电议
10mM * 1mL in DMSO电议

产品名称
VQD-002,TCN-P
产品介绍

生物活性

Triciribine phosphate是一种DNA synthesis抑制剂,也抑制PC3细胞系中的Akt和CEM-SS,H9,H9IIIB,U1细胞中的HIV-1,IC50分别为130 nM和20 nM;对PI3K/PDK1没有抑制作用;作用于缺乏腺苷激酶的细胞,活性降低5000

化学数据

目录号A11033
作用机制Inhibitor (抑制剂)
M. Wt400.3
FormulaC13H17N6O7P
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.61966-08-3
SynonymsVQD-002,TCN-P
SMILESCN1C2=NC=NC3=C2C(=CN3[C@H]4[C@@H]([C@@H]([C@H](O4)COP(=O)(O)O)O)O)C(=N1)N

溶解度

In vitro (25°C)DMSO60 mg/mL (187.32 mM)
WaterInsoluble
EthanolInsoluble
In vivo1% DMSO+30% polyethylene glycol+1% Tween 8028 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM24.98 mL124.91 mL249.81 mL
0.5 mM5 mL24.98 mL49.96 mL
1 mM2.5 mL12.49 mL24.98 mL
5 mM0.5 mL2.5 mL5 mL

*The above data is based on the productmolecular weight 400.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.