生物活性
URB597是脂肪酸酰胺水解酶（FAAH）的相对选择性抑制剂。
靶点信息
化学数据
| 目录号 | A11049 |
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 338.4 |
| Formula | C20H22N2O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 546141-08-6 |
| Synonyms | KDS-4103, URB-597 |
| SMILES | C1CCC(CC1)NC(=O)OC2=CC=CC(=C2)C3=CC(=CC=C3)C(=O)N |
溶解度
| In vitro (25°C) | DMSO | 62 mg/mL (183.21 mM) |
| Water | Insoluble |
| Ethanol | 5 mg/mL (14.77 mM) |
| In vivo | 30% propylene glycol, 5% Tween 80, 65% D5W | 28 mg/mL |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 29.55 mL | 147.75 mL | 295.51 mL |
| 0.5 mM | 5.91 mL | 29.55 mL | 59.1 mL |
| 1 mM | 2.96 mL | 14.78 mL | 29.55 mL |
| 5 mM | 0.59 mL | 2.96 mL | 5.91 mL |
*The above data is based on the productmolecular weight 338.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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