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YM201636
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
YM201636图片
CAS NO:371942-69-7
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
10mM * 1mL in DMSO电议

产品名称
YM-201636
产品介绍

生物活性

YM201636是PIKfyve的细胞渗透性和选择性抑制剂(IC50 = 33 nM)。

靶点信息

PIKfyvep110α
33 nM3.3 μM

化学数据

目录号A11064
作用机制Inhibitor (抑制剂)
M. Wt467.5
FormulaC25H21N7O3
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.371942-69-7
SynonymsYM-201636
SMILESC1COCCN1C2=NC(=NC3=C2OC4=C3C=CC=N4)C5=CC(=CC=C5)NC(=O)C6=CN=C(C=C6)N

溶解度

In vitroDMSO31 mg/mL (66.3 mM)
WaterInsoluble
EthanolInsoluble
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM21.39 mL106.95 mL213.9 mL
0.5 mM4.28 mL21.39 mL42.78 mL
1 mM2.14 mL10.7 mL21.39 mL
5 mM0.43 mL2.14 mL4.28 mL

*The above data is based on the productmolecular weight 467.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.