您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Bosentan
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Bosentan
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Bosentan图片
CAS NO:147536-97-8
包装与价格:
包装价格(元)
25mg电议
50mg电议
100mg电议
200mg电议
10mM * 1mL in DMSO电议

产品介绍

生物活性

Bosentan是内皮素-1(ET-A)和内皮素B(ET-B)受体的竞争性拮抗剂。

靶点信息

ET-AET-B
4.7 nM(Ki)95 nM(Ki)

化学数据

目录号A11091
作用机制Inhibitor (抑制剂)
M. Wt551.6
FormulaC27H29N5O6S
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.147536-97-8
SMILESCC(C)(C)C1=CC=C(C=C1)S(=O)(=O)NC2=C(C(=NC(=N2)C3=NC=CC=N3)OCCO)OC4=CC=CC=C4OC

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM18.13 mL90.65 mL181.29 mL
0.5 mM3.63 mL18.13 mL36.26 mL
1 mM1.81 mL9.06 mL18.13 mL
5 mM0.36 mL1.81 mL3.63 mL

*The above data is based on the productmolecular weight 551.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.