您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > LY2109761
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
LY2109761
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
LY2109761图片
CAS NO:700874-71-1
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议
100mg电议

产品名称
LY-2109761
产品介绍

生物活性

LY2109761是一种新型的I型和II型转化生长因子β受体双重抑制剂,对Smad2的磷酸化产生负面影响,作为抑制胰腺癌转移的治疗方法。

化学数据

目录号A11133
作用机制Inhibitor (抑制剂)
M. Wt441.5
FormulaC26H27N5O2
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.700874-71-1
SynonymsLY-2109761
SMILESC1CC2=C(C(=NN2C1)C3=CC=CC=N3)C4=C5C=CC(=CC5=NC=C4)OCCN6CCOCC6

溶解度

In vitro (25°C)DMSO2 mg/mL (4.52 mM)
WaterInsoluble
EthanolInsoluble
In vivo0.5% CMC+0.25% Tween 80 (suspensions)15 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM22.65 mL113.25 mL226.5 mL
0.5 mM4.53 mL22.65 mL45.3 mL
1 mM2.27 mL11.33 mL22.65 mL
5 mM0.45 mL2.27 mL4.53 mL

*The above data is based on the productmolecular weight 441.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.