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TOK-001(Galeterone)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
TOK-001(Galeterone)图片
CAS NO:851983-85-2
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议
100mg电议
10mM * 1mL in DMSO电议

产品名称
VN/124-1
产品介绍

生物活性

TOK-001 (Galeterone)既是雄激素受体拮抗剂又是CYP17A1抑制剂。

靶点信息

CYP17Androgen Receptor
300 nM384 nM

化学数据

目录号A11138
作用机制Inhibitor (抑制剂)
M. Wt388.3
FormulaC26H32N2O
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.851983-85-2
SynonymsVN/124-1
SMILESC[C@]12CC[C@@H](CC1=CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC=C4N5C=NC6=CC=CC=C65)C)O

溶解度

In vitro (25°C)DMSO21 mg/mL (54.04 mM)
WaterInsoluble
EthanolWarmed: 36 mg/mL (92.65 mM)
In vivo0.5% hydroxyethyl cellulose28 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM25.75 mL128.77 mL257.53 mL
0.5 mM5.15 mL25.75 mL51.51 mL
1 mM2.58 mL12.88 mL25.75 mL
5 mM0.52 mL2.58 mL5.15 mL

*The above data is based on the productmolecular weight 388.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.