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CEP-18770(Delanzomib)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CEP-18770(Delanzomib)图片
CAS NO:847499-27-8
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议
100mg电议
10mM * 1mL in DMSO电议

产品名称
CEP18770
产品介绍

生物活性

CEP-18770 (Delanzomib)是一种新型口服活性蛋白酶体抑制剂,IC50为3.8 nM,具有良好的肿瘤选择性,可用于治疗对蛋白酶体抑制有反应的MM和其他恶性肿瘤。

靶点信息

Chymotrypsin-like proteasome
3.8 nM

化学数据

目录号A11145
作用机制Inhibitor (抑制剂)
M. Wt413.3
FormulaC21H28BN3O5
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.847499-27-8
SynonymsCEP18770
SMILESB([C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)C1=CC=CC(=N1)C2=CC=CC=C2)(O)O

溶解度

In vitroDMSO73 mg/mL (176.63 mM)
WaterInsoluble
Ethanol73 mg/mL (176.63 mM)
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM24.2 mL120.98 mL241.95 mL
0.5 mM4.84 mL24.2 mL48.39 mL
1 mM2.42 mL12.1 mL24.2 mL
5 mM0.48 mL2.42 mL4.84 mL

*The above data is based on the productmolecular weight 413.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.