生物活性
NVP-BVU972是一种选择性的MET抑制剂。
靶点信息
化学数据
目录号 | A11150 |
作用机制 | Inhibitor (抑制剂) |
M. Wt | 340.4 |
Formula | C20H16N6 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for36 months. In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
CAS No. | 1185763-69-2 |
Synonyms | NVPBVU972 |
SMILES | CN1C=C(C=N1)C2=NN3C(=NC=C3CC4=CC5=C(C=C4)N=CC=C5)C=C2 |
溶解度
In vitro | DMSO | 67 mg/mL (196.83 mM) |
Water | Insoluble |
Ethanol | 67 mg/mL |
*<1 mg/ml means slightly soluble or insoluble. *Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
0.1 mM | 29.38 mL | 146.89 mL | 293.77 mL |
0.5 mM | 5.88 mL | 29.38 mL | 58.75 mL |
1 mM | 2.94 mL | 14.69 mL | 29.38 mL |
5 mM | 0.59 mL | 2.94 mL | 5.88 mL |
*The above data is based on the productmolecular weight 340.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.