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A 803467
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
A 803467图片
CAS NO:944261-79-4
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议
100mg电议
10mM * 1mL in DMSO电议

产品名称
A-803467, A803467
产品介绍

生物活性

A 803467是NaV1.8通道的选择性阻滞剂(hNaV1.8,hNaV1.3,hNaV1.7,hNaV1.5和hNaV1.2通道的IC50值分别为8、2450、6740、7340和7380 nM)。

靶点信息

Na(V1.8) channel
8 nM

化学数据

目录号A11234
作用机制Blocker (阻断剂)
M. Wt357.8
FormulaC19H16ClNO4
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.944261-79-4
SynonymsA-803467, A803467
SMILESCOC1=CC(=CC(=C1)NC(=O)C2=CC=C(O2)C3=CC=C(C=C3)Cl)OC

溶解度

In vitro (25°C)DMSO64 mg/mL (178.87 mM)
WaterInsoluble
Ethanol10 mg/mL (27.95 mM)
In vivo2% DMSO+corn oil4 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM27.95 mL139.74 mL279.49 mL
0.5 mM5.59 mL27.95 mL55.9 mL
1 mM2.79 mL13.97 mL27.95 mL
5 mM0.56 mL2.79 mL5.59 mL

*The above data is based on the productmolecular weight 357.8. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.