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Belizatinib
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Belizatinib图片
CAS NO:1357920-84-3
规格:98%
分子量:577.73
包装与价格:
包装价格(元)
2mg电议
5mg电议
10mg电议
50mg电议
100mg电议

产品介绍
Belizatinib is an oral, dual, potent inhibitor of ALK and TRKA, TRKB, and TRKC, with IC50 of 0.7 nM for wild-type recombinant ALK kinase.
CAS:1357920-84-3
分子式:C33H44FN5O3
分子量:577.73
纯度:98%
存储:Store at -20°C

Background:

Belizatinib is an oral, dual, potent inhibitor of ALK and TRKA, TRKB, and TRKC, with IC50 of 0.7 nM for wild-type recombinant ALK kinase.


TSR-011 has antitumour activity in the clinical trials.


TSR-011 exerts sustained potent inhibition of ALK-dependent tumour growth in mouse models[1].


参考文献:
[1]. Sullivan I, et al. ALK inhibitors in non-small cell lung cancer: the latest evidence and developments. Ther Adv Med Oncol. 2016 Jan;8(1):32-47.